RAF Typhoon jets have joined forces with France's air force in a coordinated attack on an hidden munitions depot in Syrian territory used by the IS group, according to the UK Ministry of Defence.
The site, located using surveillance, was thought to be containing munitions and bombs, the release indicated, and was positioned in hills just north of the ancient city of Palmyra in central Syria.
"Our aircraft employed laser-guided Paveway IV weapons to strike a number of access tunnels providing entry to the facility... preliminary assessments suggest the objective was successfully hit," officials stated.
There was no indication of any harm to civilians in the attack conducted Saturday night and all the aircraft made a safe return, the defence officials confirmed.
The Typhoon fighters were supported by a Voyager refuelling tanker.
The Islamic State group - alternatively referred to as Daesh - established militant control over parts of Syria and Iraq until 2019.
"This operation demonstrates our UK leadership, and commitment to operate in unison with our partners, to stamp out any revival of IS and their harmful and extremist ideologies in the area," Britain's Defence Chief John Healey stated.
British military aircraft have conducted surveillance missions over Syrian airspace to "deter any attempted resurgence" of the group subsequent to its military defeat at the Baghuz confrontation in 2019, the ministry said.
"I extend gratitude to the personnel of our armed forces involved in this strike for their skill and their bravery," he added. "Including them were thousands of British troops stationed over Christmas and New Year. This action, to remove dangerous terrorists who threaten our security, demonstrates how UK forces are prepared to act, continuously, keeping Britain secure within its borders and strong abroad."
During December, the American forces executed what it termed a "massive strike" targeting IS targets in the country, subsequent to an assault killed two US troops and a civilian interpreter in Palmyra.
The UN says Islamic State still maintains between 5,000 and 7,000 fighters in Iraq and Syria.
